SPERMICIDAL ACTIVITY OF SURFACE-ACTIVE AGENTS

Spermicidal agents.

In recent years, there is a development of vaginal contraceptives incorporating potent spermicides. Many compounds with different pharmacological activity have been evaluated in vitro for their spermicidal activity. Drugs such as surfaceactive agents (synthetic and natural), ionophores, antiliquefying agents, antimicrobial agents and miscellaneous agents such as gossypol, Azadirachta indica, va...

Surfactants - Surface Active Agents

The definition for a detergent is a cleaning agent. The main cleaning agent used in earlier days was soap. This term means a compound formed from the reaction of a fatty acid with a base such as caustic soda, forming the sodium soap of the acid. The more commonly used cleaning agent in this day and age is the synthetic detergent (SYNDET) which is a formulation such as TIDE or FAB. The essential...

Spermicidal activity of some halides.

Though most of the metallic ions are spermicidal in action, the present investigation emphasises the spermicidal activity of anions. Among the inorganic compounds screened at 4 concentrations (0.01%, 0.1%, 1% and 5%) halides are mainly spermicidal, except NaCl, KCl & CsCl which are spermiostatic; sulphates and nitrates are mainly spermiostatic except ZnSO4 at 1% concentration and above; CuSO4, ...

Silicone Surface-Active Agents

Surface active agents as tumor promoters.

*TUC Centenary Institute of Occupational Health London School of Hygiene and Tropical Medicine, Keppel St., London WC1E-7HT, England. the types of promoter listed have not been demonstrated as such by animal experiments, but if a substance is a carcinogenic but not mutagenic, then it is most probably a tumor promoter. This assumes that mutagens are initiators and that promoters can induce cance...